Chapter 4 – Treatment of elderly patients with myeloma

Contributors: Eileen M Boyle, Charline Legrand, Hélène Demarquette, Stéphanie Guidez, Charles Herbaux, Xavier Leleu, and Thierry Facon

9 – Conclusion and perspectives

The clinical management of elderly patients with myeloma remains challenging. In addition to up-to-date knowledge of tumor biology and of treatment strategies, day-to-day practice requires an accurate assessment of many clinical and social parameters. The use of standardized frailty assessments needs to be validated in a community-based and prospective setting. Novel agents including thalidomide, lenalidomide, and bortezomib have helped to improve the outcome for elderly myeloma patients. To improve the outcome further, priority should be given to developing more effective treatment strategies and clinical trials tailored to the specific needs of these patients.