Chapter 1 – Pathophysiology

Contributors: Hervé Avet-Loiseau and Jill Corre

Multiple Choice Questionnaire

Activation of which pathway up-regulates adhesion molecules on both MSCs and MM cells?
Which high-risk chromosomal abnormalities in multiple myeloma are the most powerful?
Aside from the effects on the tumor itself, which two key features of MM are stimulated by the dialogue between BMMe and MM cells occurring during the progression of the disease?
Which treatment(s) specifically targets both the myeloma cells and the BMMe?
Multiple Choice Questionnaire: Chapter 1 – Pathophysiology
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